GNF remains committed to the public dissemination of the results of its fundamental research programs through timely scientific publication as well as open access to many of its most signficant tools and databases. Listed below are representative samples of recent GNF publications.
Please click here for a full list of GNF's publications.
Design, synthesis and biological evaluation of indole-2-carboxamides, a promising class of anti-tuberculosis agents.
Kondreddi RR, Jiricek J, Rao SP, Lakshminarayana SB, Camacho LR, Rao R, Herve M, Bifani P, Ma NL, Kuhen K, Goh A, Chatterjee AK, Dick T, Diagana TT, Manjunatha UH, Smith PW.
J Med Chem. 2013 Oct;
Structures of a Bifunctional Cell Wall Hydrolase CwlT Containing a Novel Bacterial Lysozyme and an NlpC/P60 dl-Endopeptidase.
Xu Q, Chiu HJ, Farr CL, Jaroszewski L, Knuth MW, Miller MD, Lesley SA, Godzik A, Elsliger MA, Deacon AM, Wilson IA.
J Mol Biol. 2013 Sep;
High-content analysis of three-dimensional tumor spheroids: investigating signaling pathways using small hairpin RNA.
Shane R Horman, Jeremy To, Anthony P Orth, Nicky Slawny, Meghan J Cuddihy, Diana Caracino.
Nature Methods. 2013 Sep;
3D High-Content Analysis of Spheroids: New Methodology Shown to Improve Screening.
Shane R. Horman, Jeremy To, Anthony P. Orth, Nicky Slawny, Meghan Cuddihy, Diana Caracino.
Genetic Engineering and Biotechnology News. 2013 Sep;
Identification of the Plasmodium berghei resistance locus 9 linked to survival on chromosome 9.
Bopp SE, Rodrigo E, GonzÃ¡lez-PÃ¡ez GE, Frazer M, Barnes SW, Valim C, Watson J, Walker JR, Schmedt C, Winzeler EA.
Malar J. 2013 Sep;
Activation of the Transcriptional Function of the NF-kB Protein c-Rel by O-GlcNAc Glycosylation.
Ramakrishnan P, Clark PM, Mason DE, Peters EC, Hsieh-Wilson LC, Baltimore D.
Sci Signal. 2013 Aug;
NSD2 Is Recruited through Its PHD Domain to Oncogenic Gene Loci to Drive Multiple Myeloma.
Huang Z, Wu H, Chuai S, Xu F, Yan F, Englund N, Wang Z, Zhang H, Fang M, Wang Y, Gu J, Zhang M, Yang T, Zhao K, Yu Y, Dai J, Yi W, Zhou S, Li Q, Wu J, Liu J, Wu X, Chan H, Lu C, Atadja P, Li E, Wang Y, Hu M.
Cancer Res. 2013 Oct;
An Antibody That Locks HER3 in the Inactive Conformation Inhibits Tumor Growth Driven by HER2 or Neuregulin.
Garner AP, Bialucha CU, Sprague ER, Garrett JT, Sheng Q, Li S, Sineshchekova O, Saxena P, Sutton CR, Chen D, Chen Y, Wang H, Liang J, Das R, Mosher R, Gu J, Huang A, Haubst N, Zehetmeier C, Haberl M, Elis W, Kunz C, Heidt AB, Herlihy K, Murtie J, Schuller A, Arteaga CL, Sellers WR, Ettenberg SA.
Cancer Res. 2013 Oct;
An HTS-Compatible 3D Colony Formation Assay to Identify Tumor-Specific Chemotherapeutics.
Horman SR, To J, Orth AP.
J Biomol Screen. 2013 Aug;