GNF remains committed to the public dissemination of the results of its fundamental research programs through timely scientific publication as well as open access to many of its most signficant tools and databases.  Listed below are representative samples of recent GNF publications.

Please click here for a full list of GNF's publications.

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197.
Malito E, Bursulaya B, Chen C, Surdo PL, Picchianti M, Balducci E, Biancucci M, Brock A, Berti F, Bottomley MJ, Nissum M, Costantino P, Rappuoli R, Spraggon G.
Proc Natl Acad Sci U S A. 2012 Mar; 

A sulfated carbohydrate epitope inhibits axon regeneration after injury.
Brown JM, Xia J, Zhuang B, Cho KS, Rogers CJ, Gama CI, Rawat M, Tully SE, Uetani N, Mason DE, Tremblay ML, Peters EC, Habuchi O, Chen DF, Hsieh-Wilson LC.
Proc Natl Acad Sci U S A. 2012 Mar;

Functional and structural characterization of a thermostable acetyl esterase from Thermotoga maritima.
Levisson M, Han GW, Deller MC, Xu Q, Biely P, Hendriks S, Ten Eyck LF, Flensburg C, Roversi P, Miller MD, McMullan D, von Delft F, Kreusch A, Deacon AM, van der Oost J, Lesley SA, Elsliger MA, Kengen SW, Wilson IA. Proteins. 2012 Jan;

Why are some amyloidoses systemic? Does hepatic "chaperoning at a distance" prevent cardiac deposition in a transgenic model of human senile systemic (transthyretin) amyloidosis?
Buxbaum JN, Tagoe C, Gallo G, Walker JR, Kurian S, Salomon DR.
FASEB J. 2012 Feb;

CXCR4 expression in prostate cancer progenitor cells.
Dubrovska A, Elliott J, Salamone RJ, Telegeev GD, Stakhovsky AE, Schepotin IB, Yan F, Wang Y, Bouchez LC, Kularatne SA, Watson J, Trussell C, Reddy VA, Cho CY, Schultz PG.
PLoS One. 2012 ; 7(2)

The role of Drosophila Piezo in mechanical nociception.
Kim SE, Coste B, Chadha A, Cook B, Patapoutian A.
Nature. 2012 Feb; 483(7388): 209-12.

Cofactors Required for TLR7- and TLR9-Dependent Innate Immune Responses
Chiang CY, Engel A, Opaluch AM, Ramos I, Maestre AM, Secundino I, De Jesus PD, Nguyen QT, Welch G, Bonamy GM, Miraglia LJ, Orth AP, Nizet V, Fernandez-Sesma A, Zhou Y, Barton GM, Chanda SK.
Cell Host Microbe. 2012 Mar; 11(3): 306-18.

The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasites.
Delves M, Plouffe D, Scheurer C, Meister S, Wittlin S, Winzeler EA, Sinden RE, Leroy D.
PLoS Med. 2012 Feb; 9(2)

Piezo proteins are pore-forming subunits of mechanically activated channels.
Coste B, Xiao B, Santos JS, Syeda R, Grandl J, Spencer KS, Kim SE, Schmidt M, Mathur J, Dubin AE, Montal M, Patapoutian A.
Nature. 2012 Feb; 483(7388): 176-81.

Rapid expansion of human hematopoietic stem cells by automated control of inhibitory feedback signaling.
Csaszar E, Kirouac DC, Yu M, Wang W, Qiao W, Cooke MP, Boitano AE, Ito C, Zandstra PW. Cell Stem Cell. 2012 Feb; 10(2): 218-29.