GNF Publications
GNF Publications

GNF remains committed to the public dissemination of the results of its fundamental research programs through timely scientific publication as well as open access to many of its most signficant tools and databases.  Listed below are representative samples of recent GNF publications.

Please click here for a full list of GNF's publications.

Photoactivatable Glycopolymers for the Proteome-Wide Identification of Fucose-a(1-2)-Galactose Binding Proteins.
Wibowo A, Peters EC, Hsieh-Wilson LC.
J Am Chem Soc. 2014 Jun;

KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment and prevention of disease transmission.
Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, Chen Z, Francek C, Wu T, Nagle A, Barnes SW, Plouffe D, Lee MC, Fidock DA, Graumans W, Vd Vegte-Bolmer M, V Gemert GJ, Wirjanata G, Sebayang B, Marfurt J, Russell B, Suwanarusk R, Price RN, Nosten F, Tungtaeng A, Gettayacamin M, Sattabongkot J, Taylor J, Walker JR, Tully D, Patra KP, Flannery EL, Vinetz JM, Renia L, Sauerwein RW, Winzeler EA, Glynne RJ, Diagana TT.
Antimicrob Agents Chemother. 2014 Jun;

Erratum: Corrrection to Discovery of Tetrahydropyrazolopyrimidine Carboxamide Derivatives As Potent and Orally Active Novel Antitubercular Agents.
Yokokawa F, Wang G, Chan WL, Ang SH, Wong J, Ma I, Rao SP, Manjunatha U, Lakshminarayana SB, Herve M, Kounde C, Tan BH, Thayalan P, Dick T, Ng SH, Nanjundappa M, Ravindran S, Gee P, Tan M, Wei L, Goh A, Chen PY, Lee KS, Zhang C, Wagner T, Dix I, Chatterjee A, Pethe K, Kuhen K, Glynne R, Smith P, Bifani P, Jiricek J.
ACS Med Chem Lett. 2014 Apr; 5(4): 451.

Molecular characterization of novel pyridoxal-5'-phosphate-dependent enzymes from the human microbiome.
Fleischman NM, Das D, Kumar A, Xu Q, Chiu HJ, Jaroszewski L, Knuth MW, Klock HE, Miller MD, Elsliger MA, Godzik A, Lesley SA, Deacon AM, Wilson IA, Toney MD.
Protein Sci. 2014 May;

High Throughput Mutagenesis for Identification of Residues Regulating Human Prostacyclin (hIP) Receptor Expression and Function.
Bill A, Rosethorne EM, Kent TC, Fawcett L, Burchell L, van Diepen MT, Marelli A, Batalov S, Miraglia L, Orth AP, Renaud NA, Charlton SJ, Gosling M, Gaither LA, Groot-Kormelink PJ.
PLoS One. 2014 ; 9(6)

Discovery, Optimization, and Biological Evaluation of 5-(2-(trifluoromethyl)phenyl)-indazoles as a Novel Class of Transient Receptor Potential A1 (TRPA1) Antagonists.
Rooney L, Vidal A, D'Souza AM, Devereux N, Masick B, Boissel V, West R, Head V, Stringer R, Lao J, Petrus MJ, Patapoutian A, Nash M, Stoakley N, Panesar M, Verkuyl JM, Schumacher AM, Petrassi HM, Tully DC.
J Med Chem. 2014 Jun;

Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner.
Sipilä K, Haag S, Denessiouk K, Käpylä J, Peters EC, Denesyuk A, Hansen U, Konttinen Y, Johnson MS, Holmdahl R, Heino J.
FASEB J. 2014 May;

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six.
Jabba S, Goyal R, Sosa-Pagán JO, Moldenhauer H, Wu J, Kalmeta B, Bandell M, Latorre R, Patapoutian A, Grandl J.
Neuron. 2014 Jun; 82(5): 1017-31.

Heterogeneous Hydration of p53/MDM2 Complex.
Guo Z, Li B, Dzubiella J, Cheng LT, McCammon JA, Che J.
J Chem Theory Comput. 2014 Mar; 10(3): 1302-1313.

Discovery of structurally novel, potent and orally efficacious GPR119 agonists.
Alper P, Azimioara M, Cow C, Mutnick D, Nikulin V, Michellys PY, Wang Z, Reding E, Paliotti M, Li J, Bao D, Zoll J, Kim Y, Zimmerman M, Groessel T, Tuntland T, Joseph SB, McNamara P, Seidel HM, Epple R.
Bioorg Med Chem Lett. 2014 May; 24(10): 2383-7.