The successful candidate will play an important role in existing drug discovery projects and in initiating new lead discovery projects targeting established and novel molecular pathways.  

Responsibilities:
•Identifying and proposing new drug discovery targets
•Developing and optimizing biochemical or cell-based assays for hit identification and lead optimization
•Profiling SAR medchem compounds in primary and secondary in vitro assays for lead optimization
•Identifying and implementing technologies and approaches that will enable the identification of small molecule modulators of cell surface receptor or intracellular targets with desired activities
•Providing project leadership from hit-to-lead to preclinical candidate selection by working and coordinating efforts with multi-disciplinary groups including medicinal chemistry, in vitro/in vivo ADME and in vivo pharmacology

Requirements:
•A broad-based understanding of mammalian cell signal transduction and a detailed knowledge of cutting-edge molecular, biochemical and cellular drug discovery approaches 
•A Ph.D. in a relevant field with 6+ years of relevant post-doctoral work and a demonstrated record of scientific achievement
•Prior drug discovery and supervisory experience in a biotech or pharma setting is highly desirable

Send CV/resume as attachment to the email address listed below (please include job code).