- Vercammen D, Belenghi B, van de Cotte B, Beunens T, Gavigan J-A, De Rycke R, Brackenier A, Inze D, Harris JL, Van Breusegem F. Serpin 1 of Arabidopsis thaliana is a suicide inhibitor of metacaspase 9. J Mol Biol 2006; (In Press).
- Urbina HD, Debaene F, Jost B, Bole-Feysot C, Mason DE, Kuzmic P, Harris JL, Winssinger N. Self-Assembled small-molecule microarrays for protease screening and profiling. 2006; (In Press).
- Tully DC, Liu H, Chatterjee AK, Alper PB, Williams JA, Roberts MJ, Mutnick D, Woodmansee DH, Hollenbeck T, Gordon P, et al. Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors. Bioorg Med Chem Lett 2006;16(19):5107-11.
- Tully DC, Liu H, Chatterjee AK, Alper PB, Epple R, Williams JA, Roberts MJ, Woodmansee DH, Masick BT, Tumanut C, et al. Synthesis and SAR of arylaminoethyl amides as noncovalent inhibitors of cathepsin S: P3 cyclic ethers. Bioorg Med Chem Lett 2006;16(19):5112-7.
- Tully DC, Liu H, Alper PB, Chatterjee AK, Epple R, Roberts MJ, Williams JA, Nguyen KT, Woodmansee DH, Tumanut C, et al. Synthesis and evaluation of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 3: heterocyclic P3. Bioorg Med Chem Lett 2006;16(7):1975-80.
- Alper PB, Liu H, Chatterjee AK, Nguyen KT, Tully DC, Tumanut C, Li J, Harris JL, Tuntland T, Chang J, et al. Arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Optimization of P1 and N-aryl. Bioorg Med Chem Lett 2006;16(6):1486-1490.
- Winssinger N, Harris JL. Microarray-based functional protein profiling using peptide nucleic acid-encoded libraries. Expert Rev Proteomics 2005;2(6):937-947.
- Petrassi HM, Williams JA, Li J, Tumanut C, Ek J, Nakai T, Masick B, Backes BJ, Harris JL. A strategy to profile prime and non-prime proteolytic substrate specificity. Bioorg Med Chem Lett 2005;15(12):3162-6.
- Liu H, Tully DC, Epple R, Bursulaya B, Li J, Harris JL, Williams JA, Russo R, Tumanut C, Roberts MJ, et al. Design and synthesis of arylaminoethyl amides as noncovalent inhibitors of cathepsin S. Part 1. Bioorg Med Chem Lett 2005;15(22):4979-84.
- Li J, Lim SP, Beer D, Patel V, Wen D, Tumanut C, Tully DC, Williams JA, Jiricek J, Priestle JP, et al. Functional profiling of recombinant NS3 proteases from all four serotypes of dengue virus using tetrapeptide and octapeptide substrate libraries. J Biol Chem 2005;280(31):28766-74.
- Harris JL, Winssinger N. PNA encoding (PNA=peptide nucleic acid): from solution-based libraries to organized microarrays. Chemistry 2005;11(23):6792-801.
- Winssinger N, Damoiseaux R, Tully DC, Geierstanger BH, Burdick K, Harris JL. PNA-encoded protease substrate microarrays. Chem Biol 2004;11(10):1351-60.
- Shipway A, Danahay H, Williams JA, Tully DC, Backes BJ, Harris JL. Biochemical characterization of prostasin, a channel activating protease. Biochem Biophys Res Commun 2004;324(2):953-63.
- Mason DE, Ek J, Peters EC, Harris JL. Substrate profiling of deubiquitin hydrolases with a positional scanning library and mass spectrometry. Biochemistry 2004;43(21):6535-44.
- Harris J, Mason DE, Li J, Burdick KW, Backes BJ, Chen T, Shipway A, Van Heeke G, Gough L, Ghaemmaghami A, et al. Activity profile of dust mite allergen extract using substrate libraries and functional proteomic microarrays. Chem Biol 2004;11(10):1361-72.
- Debaene F, Mejias L, Harris JL, Winssinger N. Synthesis of a PNA-encoded cysteine protease inhibitor library. Tetrahedron 2004;60(39):8677-8690.
- Wang CC, Bozdech Z, Liu CL, Shipway A, Backes BJ, Harris JL, Bogyo M. Biochemical analysis of the 20 S proteasome of Trypanosoma brucei. J Biol Chem 2003;278(18):15800-8.
- Winssinger N, Ficarro S, Schultz PG, Harris JL. Profiling protein function with small molecule microarrays. Proc Natl Acad Sci U S A 2002;99(17):11139-44.
- Winssinger N, Harris JL, Backes BJ, Schultz PG. From split-pool libraries to spatially addressable microarrays and its application to functional proteomic profiling. Angew Chem, Int Ed Engl 2001;40(17):3152-3155.
- Harris JL, Alper PB, Li J, Rechsteiner M, Backes BJ. Substrate specificity of the human proteasome. Chem Biol 2001;8(12):1131-41.
