Principal Scientist I/II – Cancer Therapeutics / Novartis - GNF

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Principal Scientist I/II – Cancer Therapeutics / Novartis - GNF

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4 FDA approved drugs; 15+ clinical candidates; 400+ patents; 21 years of GNF history!

At GNF, the mission of the Cancer Therapeutics Department is to discover safe and effective therapeutics for oncology indications. We are recruiting a Principal Scientist I or II to design and execute novel drug discovery programs using our state-of-the-art platforms and cutting-edge technologies. The successful candidate will have a strong background in cancer biology and extensive in vitro laboratory experience. He or she may line manage one or more associates and will collaborate effectively within highly-matrixed multidisciplinary teams to deliver first-in-class small molecule or biologic clinical candidates. Preference will be given to candidates with deep expertise in cancer cell-autonomous pathways.

Responsibilities will include, but are not limited to:

 Utilize GNF and Novartis state-of-the-art technologies and strengths of expertise to design first-in-class cancer drug discovery projects
 Develop and drive drug discovery projects in collaboration with colleagues in bioinformatics, chemistry, in vivo pharmacology, high-throughput screening, biologics/biotherapeutics, pharmacokinetics, engineering, project management, and other disciplines as appropriate
 Lead the design, development, and execution of in vitro cellular and biochemical assays
 Present strategies and results regularly to colleagues, management, and other stakeholders
 Contribute to discussions of ongoing and proposed drug discovery projects and approaches
 Potentially line manage one or more direct reports, DOE

What you’ll bring to the role:

 Ph.D. in cancer biology or a related field
 3+ years of post-doctoral experience (industry or academia)
 Experience and/or publication record demonstrating a deep understanding of cancer biology, thorough knowledge of current related literature, and familiarity with cutting edge laboratory methodologies
 Fluency in cell biology bench techniques, biochemical assays, and relevant software; molecular biology, profiling, and data-mining experience preferred
 Strong scientific and organizational leadership skills
 Innovation and scientific creativity; the ability to address challenging biological problems with scientifically sound approaches
 Outstanding communication, collaboration, and mentoring skills
 A desire to make a positive impact in a highly-interactive and fast-paced environment
 A commitment to excellence, quality, and integrity

Why consider Novartis?

We believe the answers are found when curious, courageous, and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks. And where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help s reimagine medicine.

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.



Business Unit





San Diego, CA

Company/Legal Entity


Functional Area

Research & Development

Job Type

Full Time

Employment Type


Shift Work