Protein Scientist, Biologics Discovery - Novartis / GNF

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Protein Scientist, Biologics Discovery - Novartis / GNF

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4 FDA approved drugs; 15+ clinical candidates; 400+ patents; 21 years of GNF history!

The Biologics Discovery group at GNF is seeking a highly motivated protein scientist. This is a great opportunity to join a group dedicated to protein and antibody drug discovery and optimization and work with multidisciplinary drug discovery teams in a variety of disease areas.

Your responsibilities:

• Plan and execute cloning, expression and purification of proteins (including), using microbial and eukaryotic hosts
• Characterize antibodies and proteins with standard methodologies, including binding assays
• Contribute to analysis and synthesis of results, design of new experiments and clear communication of progress to the project team(s)
• Work effectively as a member of cross-functional teams to accomplish shared project goals
• Contemporaneous and accurate documentation of experiments[#video#https://youtu.be/6zHT-WPPFLY{#400,300#}#/video#]

What you will bring to the role:

• BS/MS degree in biology, biochemistry, molecular biology, immunology, or related discipline with 4+ years of academic or industry laboratory experience
• Proficiency in molecular biology techniques for the generation of plasmid constructs for protein and antibody recombinant expression and use of standard DNA software
• Experience with standard protein biochemistry techniques such as SDS-PAGE, antibody and protein purification, interpretation of MS and biophysical measurements
• Attention to detail, ability to communicate effectively, and an eagerness to learn new things


• Experience with any of the following: flow cytometry, cell culture, cell line generation, cell-based assays, protein/antibody labeling
• Knowledge of antibody discovery through hybridoma or display techniques
• Experience with expressing and characterizing recombinant enzymes, including optimization of enzymatic assays
• Ability to analyze experiments in related software such as Microsoft Excel, including basic macro programing; FlowJo; Octet

Why consider Novartis?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.



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San Diego, CA

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Functional Area

Research & Development

Job Type

Full Time

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Shift Work