Principal Scientist Discovery Chemistry Novartis GNF San Diego

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Principal Scientist Discovery Chemistry Novartis GNF San Diego

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4 FDA approved drugs; 15+ clinical candidates; 400+ patents; 1000+ peer-reviewed articles

We are seeking an exceptionally talented and highly motivated synthetic chemist to join our Discovery Chemistry department. As a new Principal Scientist I/II you will contribute to the identification of the next wave of clinical candidates and FDA approved drugs from GNF. You will be part of a multidisciplinary team that advances the boundaries of science and you will productively and creatively apply synthetic organic expertise and techniques to shape the directions of our enabling technologies and innovative drug discovery projects. In addition, you will influence other department activities, solve problems and advise others on their key decision-making experiments.

Your responsibilities include, but are not limited to:

 Apply expertise in synthetic organic chemistry to advance new drug discovery approaches and projects at all stages
 Independently evaluate the scientific potential of new methodologies, technologies and concepts, and expand their appropriate application across the department/institute
 Work independently in a highly dynamic environment and effectively collaborate with colleagues from other scientific disciplines, including medicinal chemistry, molecular modeling, chemical biology, structural biology, biophysics, biochemistry, in vitro/in-vivo metabolism and pharmacokinetics, pharmacology and disease biology to advance drug discovery projects
 Perform experimental work including the design and execution of synthetic schemes to access key target molecules or intermediates
 Critically analyze chemical and biological data in order to design new chemical structures or approaches that address key issues for the project
 Maintain an exceptional, state of the art, expertise in synthetic organic chemistry; evaluate and implement new technologies, techniques, reactions and concepts; publish and lecture at internal and external meetings[#video#https://youtu.be/6zHT-WPPFLY{#400,300#}#/video#]

What you will bring to the role:

 PhD and postdoc in synthetic organic chemistry
 Excellent written and oral communication skills and the ability to present rationale, key data, issues and accomplishments to different audiences
 Strong expertise in the field of organic synthesis with hands on experience with a wide range of modern synthetic transformations
 Strong commitment to experimental work
 Scientific curiosity, creativity and dedication to resiliently pursue novel concepts and technologies
 Strong publication record demonstrating ability to conduct research projects independently and collaboratively
 Innovative problem solving and expertise in reaction and drug properties optimizations
 A collaborative and self-motivated style to work effectively in a fast-paced, highly integrated team environment

Desirable Requirements:

 2-5 years of industrial experience in a synthetic chemistry environment
 Mentoring and leadership experience
 Experience working in teams in a matrixed environment
 Experience with process/scale-up chemistry

Why consider Novartis?

We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.

We are Novartis. Join us and help us reimagine medicine.

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.



Business Unit





San Diego, CA

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Functional Area

Research & Development

Job Type

Full Time

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Shift Work